Browsing by Author "Silva, Helena"
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- Antioxidant activity evaluation from Artemisia gorgonum extractsPublication . Rodrigues, Neidy; Pinto, Diana C. G. A.; Seca, Ana M. L.; Silva, Helena; Pereira, M. LourdesArtemisia gorgonum (Asteraceae) known as “losna or lorna” is used in Cape Verde in traditional medicine to treat inflammation, fever and gastroenteritis. The antioxidant activity of methanol, 70% ethanol, chloroform-methanol and chloroform extracts from A. gorgonum leaves was evaluated using the DPPH assay and the results presented.
- Compounds identified on hexane and dichloromethane extracts of Salicornia ramosissimaPublication . Isca, Vera M. S.; Seca, Ana M. L.; Pinto, Diana C. G. A.; Silva, Artur M. S.; Silva, HelenaSalicornia ramosissima J. Woods (common purple glasswort) is an annual halophyte, widely distributed in the salt marsh of Ria de Aveiro (Portugal), that belongs to the Salicornia L. genus (Chenopodiaceae).[4] Although phytochemical studies genus on this genus report the presence of compounds which are well-recognized for their biological activities, such as flavonoids, chromones and alkaloids,[3] too little is known about secondary metabolites on purple glasswort. In our previous work we were able to isolate and identify ethyl o-hydroxycinnamate, (E)-fatty alcohol ferulic acid and scopoletin from the dichloromethane extract of S. ramosissima aerial parts. The structure and spectroscopic characterization of some secondary metabolites isolated from dichloromethane crude extract also will be presented and discussed.
- Lipophilic profile of the edible halophyte Salicornia ramosissimaPublication . Isca, Vera M. S.; Seca, Ana M. L.; Pinto, Diana C. G. A.; Silva, Helena; Silva, Artur M. S.Salicornia ramosissima J. Woods is considered, in the Iberian Peninsula and France, a gourmet product. Nevertheless, is one of the less studied Salicornia species. In this work, GC-MS was employed to, for the first time; fully characterise the lipophilic profile of S. ramosissima and to assess the effect of natural and extra irrigation in that profile. The obtained data showed esterified and free fatty acids, fatty alcohol, sterols, alkanes and aromatic acid derivatives, being palmitic acid, tetracosanol and octacosanol the most abundant compounds. The extra irrigation increases significantly (P < 0.001) the content of esterified lipophilic compounds. Stigmastanol, 24-ethyl-δ(22)-coprostenol, several secondary fatty alcohols and dicarboxylic acids were identified for the first time in Salicornia genus. Several of the detected compounds are known to have health benefits and our results suggest that S. ramosissima should be considered as an important dietary source of lipophilic phytochemicals.
- Potential anti-inflammatory effects of Artemisia gorgonum on rat liver injury induced by CCl4Publication . Rodrigues, Neidy; Almeida, Ana Paula; Silva, Helena; Pinto, Diana C. G. A.; Seca, Ana M. L.; Pereira, M. LourdesArtemisia gorgonum (Asteraceae) is a common traditional Cape Verde medicinal plant which has been used intensively to treat several inflammatory diseases. However, the most recent studies reported the anti-malaria activity [1], antiviral, anti-tumoral, anti-pyretic, anti-hemorrhagic, anti-coagulant, anti-fungal, anti-microbial, anti-oxidant, anti-malarial, anti-ulcerogenic and antispasmodic and hepatoprotective activities have been reported for the Artemisia genus [1–5]. Therefore, our aim is to investigate the protective effect of hydroethanolic extract of A. gorgonum (AEAG) against liver injury on rat model. […].
- Salicornia ramosissima an edible halophyte with nutritional value and a source of a unique natural compoundPublication . Isca, Vera M. S.; Seca, Ana M. L.; Pinto, Diana C. G. A.; Silva, Helena; Silva, Artur M. S.PURPOSE: Salicornia ramosissima J. Woods aerial parts are considered, in the Iberian Peninsula and France, a gourmet product mainly because of its salty taste. Nevertheless, its metabolomic profile is still unknown. As a part of our continuing search for structurally interesting natural products from plants, the aerial parts of S. ramosissima were phytochemically investigated.
- Salicornia ramosissima: secondary metabolites and testicular protection induced by ethanol extractPublication . Ferreira, Daniela; Isca, Vera M. S.; Seca, Ana M. L.; Pereira, M. Lourdes; Silva, Helena; Pinto, Diana C. G. A.; Silva, Artur M. S.The structure and spectroscopic characterization of the isolated compounds from etanol and dichloromethane extracts (PUFA omega3 ethylated, sterol and a rare wax) will be presented and discussed. Concerning the effect of ethanolic extract on mice testicular tissue under carbon tetrachloride exposure, it was clearly demonstrated that ethanol extract had a protective effect.
- Some aromatic compounds from dichloromethane extract of Salicornia ramosissima.Publication . Isca, Vera M. S.; Seca, Ana M. L.; Pinto, Diana C. G. A.; Silva, Artur M. S.; Silva, HelenaSalicornia ramosissima J. Woods, is an annual halophyte, confined to saline habitats, widely distributed in the salt marsh of Ria de Aveiro (Portugal) and also present in many salt marshes of the Iberian Peninsula. Our interest in the phytochemical study of this specie, which belongs to the genus Salicornia and family Chenopodiaceae, is based on previous knowledge that plants of this genus presented compounds such as flavonoids, chromones and alkaloids which are well-recognized for their biological activities. Salicornia ramosissima was subject to some studies of growth conditions and salinity, but its phytochemical composition remains unknown. The analysis of the dichloromethane extract from S. ramosissima aerial parts allowed the isolation of some aromatic compounds, from which we present here their unequivocal structure elucidation.