Bovine Milk Formula Based on Partial Hydrolysis of Caseins by Bromelain Enzyme : Better Digestibility and Angiotensin-Converting Enzyme-Inhibitory Properties

Medeiros, Vera; Rainha, Nuno; Paiva, Lisete S.; Lima, Elisabete; Baptista, José

http://hdl.handle.net/10400.3/6252

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Abstract(s)

A new methodology was developed using bromelain as a proteolytic enzyme for the production of a partially hydrolyzed bovine milk formula, without changing the milk's organoleptic and nutritional properties. This study also revealed that the in vitro angiotensin-converting enzyme inhibition increased in the modified milk as compared with the control sample, showing the highest angiotensin-converting enzyme-inhibitory activity for fractions with molecular weights between 3 and 10 kg mol⁻¹. The Lineweaver-Burk plot revealed that the produced milk formula acted as a non-competitive inhibitor, as determined by high performance liquid chromatography.

Keywords

ACE-inhibitory Activity Bromelain Milk Protein Allergy Partially Hydrolyzed Bovine Milk Formula Physicochemical and Microbiological Properties Rp-Hplc/Uv Sensory Analysis

URI

http://hdl.handle.net/10400.3/6252

Citation

Medeiros, V., Rainha, N., Paiva, L., Lima, E., & Baptista, J. (2013). Bovine milk formula based on partial hydrolysis of caseins by bromelain enzyme: Better digestibility and angiotensin-converting enzyme-inhibitory properties. “International Journal of Food Properties”, 17(4), 806–817. https://doi.org/10.1080/10942912.2012.675607