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Bio-Guided Optimization of Cystoseira abies-marina Cosmeceuticals Extraction by Advanced Technologies

2022-12Journal article Open access
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dc.contributor.authorRosa, Gonçalo P.
dc.contributor.authorPeixoto, Andreia F.
dc.contributor.authorBarreto, Maria do Carmo
dc.contributor.authorSeca, Ana M. L.
dc.contributor.authorPinto, Diana C. G. A.
dc.date.accessioned2023-01-16T10:46:54Z
dc.date.available2023-01-16T10:46:54Z
dc.date.issued2022-12
dc.description.abstractCystoseira abies-marina (reclassified as Gongolaria abies-marina) is a brown seaweed species rich in meroterpenoids, presenting interesting antioxidant, antitumor, and anti-inflammatory activities. However, there is still a lot to uncover regarding the bioactive potential of this species, as evidenced by the lack of records of antiaging activities from Cystoseira abies-marina, making this macroalga an excellent candidate for studies of its cosmeceutical potential. Ultrasound-(UAE) and microwave-assisted extraction (MAE) are advanced sustainable technologies that are very efficient in enhancing bioactive compound extraction. Applying these extraction techniques to a new biological matrix often calls for optimizing the parameters toward the best extraction yield. Since Cystoseira abies-marina is a new matrix for both UAE and MAE techniques, the present work proposes the optimization of the extraction process, using a novel approach: instead of only focusing on increasing the yield, the goal of this work is to determine the parameters for UAE and MAE that lead to extracts with better antiaging activities. For this bio-guided approach, several Cystoseira abies-marina extracts were prepared by UAE and MAE under varying conditions of solvent, time, and algae/solvent ratios. Their antiaging activities were then determined, and all the results combined to unveil the conditions yielding extracts with higher cosmeceutical potential. Using statistical tools, it was found that, for UAE, the best conditions were ethyl acetate, 15 min, and a ratio of 1:4, which led to an extract with high yield, and causing the strong inhibition of tyrosinase and elastase. In turn, ethanol, 10 min, and a ratio of 1:4 were the best conditions for MAE, leading to the extract with the best antioxidant activity. The results show that the proposed bio-guided approach was effective in obtaining extracts with high cosmeceutical potential, unveiling the possibility of modulating an extract’s activity by changing the extraction method.en
dc.description.sponsorshipFUNDING: Thanks are due to FCT—Fundação para a Ciência e a Tecnologia for supporting G.P.R.’s grant (SFRH/BD/144446/2019), through National and European Funds and co-financed by the European Social Fund through the Regional Operational Programme Centro 2020, as well as to FCT, the European Union, QREN, FEDER, and COMPETE, through funding the cE3c center (UIDB/00329/2020). This work received financial support from PT National Funds (FCT/MCTES, Fundação para a Ciência e a Tecnologia and Ministério da Ciência, Tecnologia e Ensino Superior) through projects UIDB/50006/2020 and UIDP/50006/2020. A.F.P. thanks FCT for funding through the Individual Call to Scientific Employment Stimulus (2020.01614.CEECIND/CP1596/CT0007).en
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationRosa, G.P., Peixoto, A.F., Barreto, M.C., Seca, A.M.L. & Pinto, D.C.G.A. (2023). Bio-Guided Optimization of Cystoseira abies-marina Cosmeceuticals Extraction by Advanced Technologies. "Marine Drugs", 21(1):35. DOI:10.3390/md21010035.en
dc.identifier.doi10.3390/md21010035pt_PT
dc.identifier.issn1660-3397
dc.identifier.urihttp://hdl.handle.net/10400.3/6556
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relationValorização eco-sustentável de Cystoseira abies-marina e Caulerpa webbiana.
dc.relationCentre for Ecology, Evolution and Environmental Changes
dc.relationAssociated Laboratory for Green Chemistry - Clean Technologies and Processes
dc.relationAssociated Laboratory for Green Chemistry - Clean Technologies and Processes
dc.relationBio-based amines from renewable resources through catalytic sustainable processes (BIO2BIA)
dc.relation.publisherversionhttps://www.mdpi.com/1660-3397/21/1/35pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectCystoseira abies-marinapt_PT
dc.subjectGongolaria abies-marinapt_PT
dc.subjectUltrasounden
dc.subjectMicrowaveen
dc.subjectCosmeceutical Potentialen
dc.titleBio-Guided Optimization of Cystoseira abies-marina Cosmeceuticals Extraction by Advanced Technologiesen
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleValorização eco-sustentável de Cystoseira abies-marina e Caulerpa webbiana.
oaire.awardTitleCentre for Ecology, Evolution and Environmental Changes
oaire.awardTitleAssociated Laboratory for Green Chemistry - Clean Technologies and Processes
oaire.awardTitleAssociated Laboratory for Green Chemistry - Clean Technologies and Processes
oaire.awardTitleBio-based amines from renewable resources through catalytic sustainable processes (BIO2BIA)
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F144446%2F2019/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00329%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F50006%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F50006%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/CEEC IND 3ed/2020.01614.CEECIND%2FCP1596%2FCT0007/PT
oaire.citation.conferencePlaceSwitzerlanden
oaire.citation.issue(1)pt_PT
oaire.citation.titleMarine Drugsen
oaire.citation.volume21pt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStreamCEEC IND 3ed
person.familyNameRosa
person.familyNameBarreto
person.familyNameSeca
person.givenNameGonçalo
person.givenNameMaria do Carmo
person.givenNameAna
person.identifier.ciencia-idC512-A6FD-4A68
person.identifier.ciencia-id4518-FF32-251F
person.identifier.orcid0000-0002-0706-8505
person.identifier.orcid0000-0001-5797-8913
person.identifier.orcid0000-0002-7709-2375
person.identifier.ridN-8704-2015
person.identifier.ridE-5475-2013
person.identifier.scopus-author-id7004455600
person.identifier.scopus-author-id6603279232
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
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project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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