Organic compounds isolated from Juniperus brevifolia bark

Vieira, Amélia; Martins, Marcele; Seca, Ana M. L.; Pinto, Diana C. G. A.; Silva, Artur M. S.

Publication

Organic compounds isolated from Juniperus brevifolia bark

2013-09Conference object

dc.contributor.author	Vieira, Amélia
dc.contributor.author	Martins, Marcele
dc.contributor.author	Seca, Ana M. L.
dc.contributor.author	Pinto, Diana C. G. A.
dc.contributor.author	Silva, Artur M. S.
dc.date.accessioned	2014-03-31T10:47:14Z
dc.date.available	2014-03-31T10:47:14Z
dc.date.issued	2013-09
dc.description	10º Encontro Nacional de Química Orgânica e 1º Simpósio Luso-Brasileiro de Química Orgânica, Lisboa, 4-6 Setembro de 2013	por
dc.description.abstract	In continuation of our study on the chemical characterization of endemic plants of the Azores archipelago, we have examined Juniperus brevifolia. Our interest in this plant was stimulated by the wide range of biological activities reported for other species of this genus and/or of their constituents. Previous work showed that leaves extracts, for instance dichloromethane extract and chloroform-soluble fraction of the acetone extract, showed high activity against HeLa and Hep-2 tumour cell lines. Chemical investigation of these extracts afforded more than thirty compounds, mainly abietane and pimarane derivatives, eight of them were new natural compounds and other exhibit interesting antitumor activity.These findings prompted us to study bark extracts.	en
dc.description.sponsorship	Thanks are due to Fundação para a Ciência e a Tecnologia (FCT, Portugal), the European Union, QREN, FEDER, COMPETE, for funding the Organic Chemistry Research Unit (QOPNA) (project PEst-C/QUI/UI0062/2011) and the Portuguese National NMR Network (RNRMN). M. Martins is grateful to CNPq, Conselho Nacional de Desenvolvimento Científico e Tecnológico – Brasil, for the scholarship granted.	por
dc.identifier.citation	Vieira, A.; Martins, M.; Seca, A. M. L.; Pinto, Diana C. G. A.; Silva, A. M. S. (2013). "Organic compounds isolated from Juniperus brevifolia bark". 10º Encontro Nacional de Química Orgânica and 1º Simpósio Luso-Brasileiro de Química Orgânica, Lisboa, 4-6 Setembro de 2013, PC128, Book of Abstracts, pag. 227.	por
dc.identifier.uri	http://hdl.handle.net/10400.3/2934
dc.language.iso	eng	por
dc.peerreviewed	yes	por
dc.relation	Strategic Project - UI 62 - 2011-2012
dc.subject	Juniperus brevifolia	por
dc.subject	Diterpenes	en
dc.subject	Cupresol	en
dc.subject	Secondary Metabolites	en
dc.title	Organic compounds isolated from Juniperus brevifolia bark	en
dc.type	conference object
dspace.entity.type	Publication
oaire.awardTitle	Strategic Project - UI 62 - 2011-2012
oaire.awardURI	info:eu-repo/grantAgreement/FCT/6820 - DCRRNI ID/PEst-C%2FQUI%2FUI0062%2F2011/PT
oaire.citation.conferencePlace	Lisboa, Portugal	por
oaire.citation.endPage	227	por
oaire.citation.startPage	227	por
oaire.citation.title	10º Encontro Nacional de Química Orgânica and 1º Simpósio Luso-Brasileiro de Química Orgânica	por
oaire.fundingStream	6820 - DCRRNI ID
project.funder.identifier	http://doi.org/10.13039/501100001871
project.funder.name	Fundação para a Ciência e a Tecnologia
rcaap.rights	openAccess	por
rcaap.type	conferenceObject	por
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relation.isProjectOfPublication.latestForDiscovery	3602a12b-888b-4e2c-a2d8-d9e0faa66cf2