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Uncharted Source of Medicinal Products : The Case of the Hedychium Genus

2020-04Journal article Open access
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dc.contributor.authorTavares, Wilson R.
dc.contributor.authorBarreto, Maria do Carmo
dc.contributor.authorSeca, Ana M. L.
dc.date.accessioned2021-03-25T13:44:54Z
dc.date.available2021-03-25T13:44:54Z
dc.date.issued2020-04
dc.description.abstractA current research topic of great interest is the study of the therapeutic properties of plants and of their bioactive secondary metabolites. Plants have been used to treat all types of health problems from allergies to cancer, in addition to their use in the perfumery industry and as food. Hedychium species are among those plants used in folk medicine in several countries and several works have been reported to verify if and how effectively these plants exert the effects reported in folk medicine, studying their essential oils, extracts and pure secondary metabolites. Hedychium coronarium and Hedychium spicatum are the most studied species. Interesting compounds have been identified like coronarin D, which possesses antibacterial, antifungal and antitumor activities, as well as isocoronarin D, linalool and villosin that exhibit better cytotoxicity towards tumor cell lines than the reference compounds used, with villosin not affecting the non-tumor cell line. Linalool and α-pinene are the most active compounds found in Hedychium essential oils, while β-pinene is identified as the most widespread compound, being reported in 12 different Hedychium species. Since only some Hedychium species have been investigated, this review hopes to shed some light on the uncharted territory that is the Hedychium genus.en
dc.description.sponsorshipThis research was funded by project MACBIOPEST (MAC2/1.1a/289), program Interreg MAC 2014–2020 co-financed by DRCT (Azores Regional Government), supporting W.R. Tavares’s grant, as well as by FCT—Fundação para a Ciência e Tecnologia, the European Union, QREN, FEDER, and COMPETE, through funding the cE3c center (UIDB/00329/2020) and the LAQV-REQUIMTE (UIDB/50006/2020).en
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationTavares, W.R., Barreto, M.C. & Seca, A.M.L. (2020). Uncharted source of medicinal products, the case of the Hedychium. “Medicines”, 7, 23. DOI: 10.3390/medicines7050023.en
dc.identifier.doi10.3390/medicines7050023pt_PT
dc.identifier.issn2305-6320
dc.identifier.pmchttp://europepmc.org/articles/PMC7281329
dc.identifier.pmidhttps://www.ncbi.nlm.nih.gov/pubmed/32354114
dc.identifier.urihttp://hdl.handle.net/10400.3/5818
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relationFCT, UIDB/00329/2020pt_PT
dc.relationFCT, UIDB/50006/2020pt_PT
dc.relation.publisherversionhttps://www.mdpi.com/2305-6320/7/5/23pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectHedychiumpt_PT
dc.subjectTraditional Medicineen
dc.subjectCoronarin Dpt_PT
dc.subjectVillosinpt_PT
dc.subjectAnti-acetylcholinesteraseen
dc.subjectAntidiabeticen
dc.subjectAnti-inflammatoryen
dc.subjectAntimicrobialen
dc.subjectAntioxidanten
dc.subjectAntitumoren
dc.titleUncharted Source of Medicinal Products : The Case of the Hedychium Genusen
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceSwitzerlanden
oaire.citation.endPage23pt_PT
oaire.citation.issue(5)pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleMedicinesen
oaire.citation.volume7pt_PT
person.familyNameTavares
person.familyNameBarreto
person.familyNameSeca
person.givenNameWilson
person.givenNameMaria do Carmo
person.givenNameAna
person.identifier.ciencia-idC512-A6FD-4A68
person.identifier.ciencia-id4518-FF32-251F
person.identifier.orcid0000-0001-9817-2756
person.identifier.orcid0000-0001-5797-8913
person.identifier.orcid0000-0002-7709-2375
person.identifier.ridN-8704-2015
person.identifier.ridE-5475-2013
person.identifier.scopus-author-id7004455600
person.identifier.scopus-author-id6603279232
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication79814483-802c-4a18-8a2a-d748d5e4cd0f
relation.isAuthorOfPublicationf61a2d4d-efd3-487c-acfb-7bb7aceb55b0
relation.isAuthorOfPublication1c6b511a-fd49-4292-a8a2-b738f558eef1
relation.isAuthorOfPublication.latestForDiscovery79814483-802c-4a18-8a2a-d748d5e4cd0f

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