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Iodine Intake and Related Cognitive Function Impairments in Elementary Schoolchildren

dc.contributor.authorBailote, Helga G. B.
dc.contributor.authorLinhares, Diana P.
dc.contributor.authorCarvalho, Célia
dc.contributor.authorPrazeres, Susana
dc.contributor.authorRodrigues, Armindo
dc.contributor.authorGarcia, Patrícia
dc.date.accessioned2022-12-05T09:49:34Z
dc.date.available2022-12-05T09:49:34Z
dc.date.issued2022-10
dc.description.abstractIodine deficiency, the most common cause of preventable mental impairment worldwide, has been linked to poorer intellectual function in several studies. However, to our knowledge, no studies have been performed in moderate iodine-deficient schoolchildren using the complete form of Wechsler Intelligence Scale for Children (WISC-III; Portuguese version). The main purpose of this study was to ascertain whether moderate iodine deficiency would affect the cognitive function of schoolchildren (7–11 years old; 3rd and 4th grades). Raven’s Colored Progressive Matrices (CPM; Portuguese version) were used for measuring the intelligence quotient (IQ) of the total population (n = 256; median UIC = 66.2 μg/L), and the WISC-III was used to study two selected subgroups: one moderately iodine-deficient (n = 30) and the other with adequate iodine intake (n = 30). WISC-III was shown to be the prime instrument for cognitive function assessment among moderate iodine-deficient schoolchildren; this subgroup had a Full-Scale IQ 15.13 points lower than the adequate iodine intake subgroup, with a magnitude effect of d = 0.7 (p = 0.013). Significant differences were also registered in 6 of the 13 Verbal-Performance IQ subtests. Moderate iodine deficiency has a substantial impact on mental development and cognitive functioning of schoolchildren, with significant impairment in both Performance IQ and Verbal IQ spectrum, adversely impacting their educational performance.en
dc.description.sponsorshipDiana Linhares was supported by a post-doc fellowship from the Fundo Regional da Ciencia (Regional Government of the Azores) (M3.1.a/F/004/2018). This work was supported by FCT-Fundacao para a Ciencia e a Tecnologia, within the project UIDP/00643/2020.en
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationBailote, H.B., Linhares, D., Carvalho, C., Prazeres, S., Rodrigues, A.S. & Garcia, P. (2022). Iodine intake and related cognitive function impairments in elementary schoolchildren. Biology, 11(10), 1507. DOI:10.3390/biology11101507en
dc.identifier.doi10.3390/biology11101507pt_PT
dc.identifier.issn2079-7737
dc.identifier.pmcPMC9599038
dc.identifier.pmid36290411
dc.identifier.urihttp://hdl.handle.net/10400.3/6478
dc.identifier.wos000872162900001
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relationResearch Institute for Volcanology and Risks Assessment
dc.relation.publisherversionhttps://www.mdpi.com/2079-7737/11/10/1507pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectIodine Deficiencyen
dc.subjectIntelligenceen
dc.subjectWISC‐IIIpt_PT
dc.subjectCPMpt_PT
dc.subjectCognitive Functionen
dc.titleIodine Intake and Related Cognitive Function Impairments in Elementary Schoolchildrenen
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleResearch Institute for Volcanology and Risks Assessment
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F00643%2F2020/PT
oaire.citation.conferencePlaceSwitzerlanden
oaire.citation.issue(10)pt_PT
oaire.citation.titleBiologyen
oaire.citation.volume11pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNamedos Santos Rodrigues
person.familyNameGarcia
person.givenNameArmindo
person.givenNamePatrícia
person.identifier.ciencia-id141A-9835-FBE0
person.identifier.ciencia-id941F-888A-412F
person.identifier.orcid0000-0002-9851-5429
person.identifier.orcid0000-0003-4490-9905
person.identifier.ridM-7754-2013
person.identifier.scopus-author-id7201694062
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication375991d8-6f81-4403-902c-000634a4cfdd
relation.isAuthorOfPublication94864ead-4016-4db1-b56e-136d294db238
relation.isAuthorOfPublication.latestForDiscovery94864ead-4016-4db1-b56e-136d294db238
relation.isProjectOfPublication2b3b1fcd-6168-440e-a281-f6013fb48871
relation.isProjectOfPublication.latestForDiscovery2b3b1fcd-6168-440e-a281-f6013fb48871

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