Occurrence of Volcanogenic Inorganic Mercury in Wild Mice Spinal Cord : Potential Health Implications

Navarro-Sempere, Alicia; García, Magdalena; Rodrigues, Armindo; Garcia, Patrícia; Camarinho, Ricardo; Segovia, Yolanda

Publication

Occurrence of Volcanogenic Inorganic Mercury in Wild Mice Spinal Cord : Potential Health Implications

2021-08Journal article

dc.contributor.author	Navarro-Sempere, Alicia
dc.contributor.author	García, Magdalena
dc.contributor.author	Rodrigues, Armindo
dc.contributor.author	Garcia, Patrícia
dc.contributor.author	Camarinho, Ricardo
dc.contributor.author	Segovia, Yolanda
dc.date.accessioned	2022-11-21T17:37:23Z
dc.date.available	2022-11-21T17:37:23Z
dc.date.issued	2021-08
dc.description.abstract	Mercury accumulation has been proposed as a toxic factor that causes neurodegenerative diseases. However, the hazardous health effects of gaseous elemental mercury exposure on the spinal cord in volcanic areas have not been reported previously in the literature. To evaluate the presence of volcanogenic inorganic mercury in the spinal cord, a study was carried out in São Miguel island (Azores, Portugal) by comparing the spinal cord of mice exposed chronically to an active volcanic environment (Furnas village) with individuals not exposed (Rabo de Peixe village), through the autometallographic silver enhancement histochemical method. Moreover, a morphometric and quantification analysis of the axons was carried out. Results exhibited mercury deposits at the lumbar level of the spinal cord in the specimens captured at the site with volcanic activity (Furnas village). A decrease in axon calibre and axonal atrophy was also observed in these specimens. Given that these are relevant hallmarks in the neurodegenerative pathologies, our results highlight the importance of the surveillance of the health of populations chronically exposed to active volcanic environments.	en
dc.description.sponsorship	This research was supported by the University of Alicante VIGROB-186.	pt_PT
dc.description.version	info:eu-repo/semantics/publishedVersion	pt_PT
dc.identifier.citation	Navarro-Sempere, A., Garcia, M., Rodrigues, A., Garcia, P.V., Camarinho, R. & Segovia Y. (2022). Occurrence of volcanogenic inorganic mercury in wild mice spinal cord: potential health implications. "Biological Trace Elements Research", 200(6), 2838-2847. DOI:10.1007/s12011-021-02890-0	en
dc.identifier.doi	10.1007/s12011-021-02890-0	pt_PT
dc.identifier.eissn	1559-0720
dc.identifier.issn	0163-4984
dc.identifier.pmc	PMC9132843
dc.identifier.pmid	34415497
dc.identifier.uri	http://hdl.handle.net/10045/117285
dc.identifier.uri	http://hdl.handle.net/10400.3/6435
dc.identifier.wos	000686876200002
dc.language.iso	eng	pt_PT
dc.peerreviewed	yes	pt_PT
dc.publisher	Springer	pt_PT
dc.relation.publisherversion	https://link.springer.com/article/10.1007/s12011-021-02890-0	pt_PT
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/	pt_PT
dc.subject	Autometallography	en
dc.subject	Environmental Pollutants	en
dc.subject	Heavy Metals	en
dc.subject	Neurotoxicity	en
dc.subject	Mus musculus	pt_PT
dc.subject	Motor Neurons	en
dc.subject	Axons	en
dc.subject	Motor Neuron Diseases	en
dc.title	Occurrence of Volcanogenic Inorganic Mercury in Wild Mice Spinal Cord : Potential Health Implications	en
dc.type	journal article
dspace.entity.type	Publication
oaire.citation.conferencePlace	United States	pt_PT
oaire.citation.endPage	2847	pt_PT
oaire.citation.issue	6	pt_PT
oaire.citation.startPage	2838	pt_PT
oaire.citation.title	Biological Trace Element Research	en
oaire.citation.volume	200	pt_PT
person.familyName	dos Santos Rodrigues
person.familyName	Garcia
person.familyName	Camarinho
person.givenName	Armindo
person.givenName	Patrícia
person.givenName	Ricardo
person.identifier.ciencia-id	141A-9835-FBE0
person.identifier.ciencia-id	941F-888A-412F
person.identifier.orcid	0000-0002-9851-5429
person.identifier.orcid	0000-0003-4490-9905
person.identifier.orcid	0000-0003-1386-7204
person.identifier.rid	M-7754-2013
person.identifier.scopus-author-id	7201694062
person.identifier.scopus-author-id	55775310500
rcaap.rights	openAccess	pt_PT
rcaap.type	article	pt_PT
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