Logo do repositório
 
Publicação

Antiaging Potential of Lipophilic Extracts of Caulerpa prolifera

2025-02-14Artigo de investigação Acesso aberto
Ver registo simples
datacite.subject.fosCiências Naturais::Ciências Biológicas
dc.contributor.authorRosa, Gonçalo
dc.contributor.authorBarreto, Maria do Carmo
dc.contributor.authorSeca, Ana
dc.contributor.authorPinto, Diana
dc.contributor.editorJacobsen, Charlotte
dc.date.accessioned2026-01-22T12:39:23Z
dc.date.available2026-01-22T12:39:23Z
dc.date.issued2025-02-14
dc.description.abstractABSTRACT: The cosmeceutical industry has increasingly turned its attention to marine macroalgae, recognizing their significant bioactive potential as sources of natural compounds for skincare applications. A growing number of products now incorporate extracts or isolated compounds from various macroalgae species. However, many species remain underexplored, highlighting a valuable opportunity for further research. Among these, Caulerpa prolifera (Forsskål) J.V. Lamouroux has emerged as a promising candidate for cosmeceutical applications. This study provides the most comprehensive phytochemical assessment of C. prolifera to date, revealing its potential as a source of bioactive extracts and compounds. The analysis identified key components of its lipophilic profile, predominantly saturated and unsaturated fatty acids, alongside di-(2-ethylhexyl) phthalate—an endocrine disruptor potentially biosynthesized or bioaccumulated by the algae. While the crude extract exhibited moderate tyrosinase inhibitory activity, its overall antioxidant capacity was limited. Fractionation of the extract, however, yielded subfractions with distinct bioactivities linked to changes in chemical composition. Notably, enhanced inhibitory activities against elastase and collagenase were observed in subfractions enriched with 1-octadecanol and only traces of phthalate. Conversely, antioxidant activity diminished with the loss of specific compounds such as β-sitosterol, erucic acid, nervonic acid, and lignoceric acid. This work advances the understanding of the relationship between the chemical composition of C. prolifera and its bioactivities, emphasizing its potential as a source of cosmeceutical ingredients, leading to a more comprehensive valorization of this macroalga.eng
dc.identifier.citationRosa, G. P., Barreto, M. C., Seca, A. M. L., & Pinto, D. C. G. A. (2025). Antiaging Potential of Lipophilic Extracts of Caulerpa prolifera. Marine Drugs, 23(2), 83. DOI: 10.3390/md23020083
dc.identifier.doi10.3390/md23020083
dc.identifier.eissn1660-3397
dc.identifier.ismn1660-3397
dc.identifier.urihttp://hdl.handle.net/10400.3/8800
dc.language.isoeng
dc.peerreviewedyes
dc.publisherMDPI
dc.relationFCT—Fundação para a Ciência e a Tecnologia - G.P.R.’s grant (SFRH/BD/144446/2019)
dc.relationEuropean Social Fund - Regional Operational Programme Centro 2020
dc.relationEuropean Union, QREN, FEDER, and COMPETE, through funding the cE3c center (FCT-UIDB/00329/2020–2024 and UID/00329/2025)
dc.relationLAQV-REQUIMTE (UIDB/50006/2020 and UIDP/50006/2020)
dc.relationPortuguese NMR Network (PT NMR) - Project No. 022161 (co-financed by FEDER through COMPETE 2020, POCI and PORL, and FCT through PIDDAC)
dc.relation.hasversionhttps://www.mdpi.com/1660-3397/23/2/83
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectmacroalgae
dc.subjectphytochemical profile
dc.subjectcosmeceutical potential
dc.titleAntiaging Potential of Lipophilic Extracts of Caulerpa proliferaeng
dc.typeresearch article
dspace.entity.typePublication
oaire.citation.endPage25
oaire.citation.issue2
oaire.citation.startPage2
oaire.citation.titleMarine Drugs
oaire.citation.volume23
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameRosa
person.familyNameBarreto
person.familyNameSeca
person.givenNameGonçalo
person.givenNameMaria do Carmo
person.givenNameAna
person.identifier.ciencia-idC512-A6FD-4A68
person.identifier.ciencia-id4518-FF32-251F
person.identifier.orcid0000-0002-0706-8505
person.identifier.orcid0000-0001-5797-8913
person.identifier.orcid0000-0002-7709-2375
person.identifier.ridN-8704-2015
person.identifier.ridE-5475-2013
person.identifier.scopus-author-id7004455600
person.identifier.scopus-author-id6603279232
relation.isAuthorOfPublication848abdd5-db5c-4194-9b8a-4aada01290ce
relation.isAuthorOfPublicationf61a2d4d-efd3-487c-acfb-7bb7aceb55b0
relation.isAuthorOfPublication1c6b511a-fd49-4292-a8a2-b738f558eef1
relation.isAuthorOfPublication.latestForDiscovery848abdd5-db5c-4194-9b8a-4aada01290ce

Ficheiros

Principais
A mostrar 1 - 1 de 1
Miniatura
Nome:
P2919_Rosa_2025_MarineDrugs.pdf
Tamanho:
1.03 MB
Formato:
Adobe Portable Document Format
Ver/Abrir
Licença
A mostrar 1 - 1 de 1
Miniatura indisponível
Nome:
license.txt
Tamanho:
1.73 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Ver/Abrir

Coleções

GBA - Artigos em Revistas Internacionais / Articles in International Journals