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Selenium status and cardiovascular risk factors in populations from different portuguese regions

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dc.contributor.authorViegas-Crespo, Ana Maria
dc.contributor.authorPavão, Maria Leonor
dc.contributor.authorSantos, Víctor
dc.contributor.authorCruz, M. L.
dc.contributor.authorPaulo, O.
dc.contributor.authorLeal, J.
dc.contributor.authorSarmento, N.
dc.contributor.authorMonteiro, M. L.
dc.contributor.authorAmorim, M. F.
dc.date.accessioned2014-02-19T16:35:55Z
dc.date.available2014-02-19T16:35:55Z
dc.date.issued1996
dc.descriptionProceedings de 2 Conferências simultâneas: "International Conference on Natural Antioxidants and Lipid Peroxidation in Atherosclerosis and Cancer (ALPAC)" e "International Conference on Quality and Safety Aspects and Nutrition in Europe'95 (QSFNE), 22-25 Agosto 1995, Helsínquia, Finlândia.en
dc.description.abstractSelenium as a cofactor of glutathione peroxidase, which prevents lipid peroxidation in mammals, takes part in the direct protection of endothelial cells against reactive oxiygen species that have been implicated in atherogenesis; moreover, it is involved in the biosynthesis of arachidonic acid derivatives in platelets and in the regulation of lipoprotein cholesterol metabolism in human beings and in animal models. These aspects are relevant enough to conclude that low selenium status may be related to atherosclerosis and, consequently, to the occurrence of cardiovascular diseases. Clinical studies showed a decrease in plasma selenium of patient’s wilh congestive cardiomyopathy and/or myocardial infarction. A significant inverse correlation between plasma selenium and severity of coronary atherosclerosis was also reported in man. However, prospective epldemiological studies on the relationship between selenium and cardiovascular disease are rather controversial. The aim of this work was to compare the selenium status by determining serum levels of this element in inhabitants of two urban and one rural Portuguese regions.The relationship between serum selenium levels and generally accepted cardiovascular risk factors was also an objetive. In this context, serurn selenium and serum lipid parameters (total cholesterol, HDL cholesterol, LDL cholesterol and triglycerides) were evaluated. Age and sex as well as alcohol and tobacco consumption were also considered.en
dc.identifier.citationVIEGAS-CRESPO, A. M., PAVÃO, M. L., SANTOS, V., CRUZ, M. L., PAULO, O., LEAL, J., SARMENTO, N., MONTEIRO, M. L., AMORIM, M. F., HALPERN, M. J. e NÈVE, J. (1996). "Selenium status and cardiovascular risk factors in populations from different portuguese regions", Selenium Intake and Status of various populations. In Natural Antioxidants and Food Quality in Atherosclerosis and Cancer Prevention, editado por J. Kumpulainen e J. Salonen (Cambridge: The Royal Society of Chemistry), pp. 188-194.en
dc.identifier.isbn0-85404-721-2
dc.identifier.urihttp://hdl.handle.net/10400.3/2793
dc.language.isoengpor
dc.publisherThe Royal Society of Chemistrypor
dc.subjectAtherosclerosisen
dc.subjectCardiovascular Risk Factorsen
dc.subjectSeleniumen
dc.titleSelenium status and cardiovascular risk factors in populations from different portuguese regionsen
dc.typebook part
dspace.entity.typePublication
oaire.citation.conferencePlaceCambridge, UKpor
oaire.citation.endPage194por
oaire.citation.startPage188por
oaire.citation.titleNatural Antioxidants and Food Quality in Atherosclerosis and Cancer Preventionen
rcaap.rightsopenAccesspor
rcaap.typebookPartpor

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