Interaction between glutathione and protopine alkaloid

Barreto, Maria do Carmo; Arrabaça, João Daniel; Pavão, Maria Leonor; Pinto, Ruy Eugénio

http://hdl.handle.net/10400.3/2812

Use this identifier to reference this record.

Name:	Description:	Size:	Format:
Interaction between glutathione and protopoine alkaloid.pdf		2.05 MB	Adobe PDF	Download

Send Feedback

Authors

Barreto, Maria do Carmo

Arrabaça, João Daniel

Pavão, Maria Leonor

Pinto, Ruy Eugénio

Abstract(s)

In previous s.rudies, glutathione decreased the inhibition of mitochondrial NADH dehydrogenase by protopine alkaloid. This fact suggests the possibility of fonnation of a complex between glutathione and protopine, decreasing the effectivc concentration of inhibitor in the reaction medium. Absorption spectra of glutathione in the absence and in the presence o f protopine corroborare this hypothesis. Changes in the UV spectrum of glutathione in the prescnce of protopine were detected, and the rate of change with time was monitored.

Description

Resumo de Comunicação em painel (POTH-030) apresentada em "27th Meeting of the Federation of European Biochemical Societies (FEBS)", 30Jun-6Jul, 2001, Lisboa, Portugal.

Keywords

Glutathione NADH Dehydrogenase Protopine Alkaloid

URI

http://hdl.handle.net/10400.3/2812

Citation

BARRETO, M. C., ARRABAÇA, J. D. C., PAVÃO, M. L. e PINTO, R. E. (2001). "Interaction between glutathione and protopine alkaloid", 27th Meeting of the Federation of European Biochemical Societies, Lisboa, Portugal, 30 de Junho - 6 de Julho (Resumo: The European Journal of Biochemistry, 2001, 268(S1), 262, POTH-030.)