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A new strategy for the synthesis of 3-cinnamoyl-2-styrylchromones and their transformation into new xanthenodiones derivatives

dc.contributor.authorPinto, Diana C. G. A.
dc.contributor.authorSeca, Ana M. L.
dc.contributor.authorLeal, Stephanie B.
dc.contributor.authorSilva, Artur M. S.
dc.contributor.authorCavaleiro, José A. S.
dc.date.accessioned2014-03-28T13:21:01Z
dc.date.available2014-03-28T13:21:01Z
dc.date.issued2011-08
dc.description23rd ISHC Congress will be held in Glasgow, Scotland from July 31 August 4, 2011.por
dc.description.abstractChromones are a class of oxygen heterocyclic compounds widely distributed in Nature. 2-Styrylchromones are, however, a small and rare naturally occurring chromones; only three derivatives have been isolated, two from the marine blue green algae Chrysophaeum taylori1 and one from the rhizomes of Imperata cylindrical. Even so, 2-styrylchromone derivatives are associated with noticeable biological activities. Our group has also been interested in the synthesis and biological evaluation of 3-aroylflavones and found that 3’,4’,5,7-tetrahydroxy-3-(3,4-dihydroxybenzoyl)flavone is a potential antioxidant agent. As part of our continuing work on the synthesis and antioxidant evaluations of polyhydroxy-2-styrylchromones,4 we set up a program aiming the synthesis of 3-cinnamoyl-2-styrylchromone (2) bearing hydroxyl groups, features considered essential to be good antioxidant and anti-inflammatory agents.en
dc.description.sponsorshipThanks are due to the University of Aveiro, to Fundação para a Ciência e a Tecnologia (FCT) and FEDER for funding the Organic Chemistry Research Unit. We are also grateful to the Portuguese National NMR Network (RNRMN) supported with funds from FCT.por
dc.identifier.citationPinto, Diana C. G. A.; Seca, Ana M. L.; Leal, Stéphanie B.; Silva, Artur M. S.; Cavaleiro, José A. S. (2011). "A new strategy for the synthesis of 3-cinnamoyl-2-styrylchromones and their transformation into new xanthenodiones derivatives", 23rd International Congress of Heterocyclic Chemistry”, Glasgow-UK, 31 de Julho a 4 de Agosto de 2011, P5.16, Abstract Book, pag. 304.en
dc.identifier.urihttp://hdl.handle.net/10400.3/2922
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherInternational Society of Heterocyclic Chemistry (ISHC)en
dc.subjectXanthenodionespor
dc.subjectSynthesisen
dc.titleA new strategy for the synthesis of 3-cinnamoyl-2-styrylchromones and their transformation into new xanthenodiones derivativesen
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceGlasgow, Scotland, UKen
oaire.citation.endPage304por
oaire.citation.startPage304por
oaire.citation.title23rd International Congress on heterocyclic Chemistryen
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor

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