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Browsing by Author "Reis, C."

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  • Serum atherogenic lipid markers in subjects from three islands of The Azores Archipelago (Portugal): a comparison study
    Publication . Ferin, Rita; Correia, Cristina; Raposo, Mafalda; Castro, Ana Rita; Reis, C.; Vieira, T.; Gonçalves, Bruno; Pavão, Maria Leonor
    São Miguel (SM), Graciosa (GR) and São Jorge (SJ) are three islands of the Azores’ Archipelago, where the death rate from coronary artery disease is abouttwice than in mainland Portugal. The aim of this study was to evaluate and compare serum atherogenic lipid markers as reflected by lipid profile, as well as by apoB/apoA-1 ratio in apparently healthy subjects from those islands. The study group was formed by 321 subjects with no chronic diseases, aged 20 to 60 years, born living in the respective island (156 from SM, 92 from GR and 73 from SJ). In all cases, about 64% of subjects were hyperlipidemic, mainly hypercholesterolemic. LDL-C and HDL-C concentrations were respectively, lower and higher in SM than in SJ or GR. ApoB concentration was 40% and 17% higher in SJ than in SM and GR, respectively, while apoA-1 reached the maximum in SM (178±38 mg/dL). Regarding apoB/apoA-1 ratio, taken as a better atherogenic marker then conventional lipid profile, subjects from GR exhibited the highest mean value (0.85±0.4), followed by those from SJ (0.75±0.3) and SM (0.58±0.2). Particularly in men from GR and SJ, ratios were 1.0 and 0.9, respectively, which corresponds to a high risk of developing a cardiovascular incident.
    2010-06Conference object Open access Show more