A Novel Short-Step Synthesis of New Xanthenedione Derivatives from the Cyclization of 3-Cinnamoyl-2-styrylchromones

Pinto, Diana C. G. A.Seca, Ana M. L.Leal, Stephanie B.Silva, Artur M. S.Cavaleiro, José A. S.2014-03-282014-03-282011Pinto, Diana; Seca, Ana; Leal, Stéphanie; Silva, Artur; Cavaleiro, José (2011). "A Novel Short-Step Synthesis of New Xanthenedione Derivatives from the Cyclization of 3-Cinnamoyl-2-styrylchromones", Synlett, 2011, 14, 2005-2008. http://dx.doi.org/10.1055/s-0030-1261172.0936-5214 (Print)1437-2096 (Online)http://hdl.handle.net/10400.3/2927Novel (E)-3-aryl-4-benzylidene-8-hydroxy-3,4-dihydro-1 H-xanthene-1,9(2H)-diones are prepared by the cyclization of (E,E)-3-cinnamoyl-5-hydroxy-2-styrylchromones efficiently catalyzed with boron tribromide. The (E,E)-3-cinnamoyl-5-hydroxy-2-styrylchromones are obtained from the Baker–Venkataraman rearrangement of (E,E)-2-acetyl-1,3-phenylene bis(3-phenylacrylate), which is greatly improved under microwave irradiation.engXanthenediones3-Cinnamoyl-5-Hydroxy-2-StyrylchromonesMicrowave IrradiationCyclizationBoron TribroA Novel Short-Step Synthesis of New Xanthenedione Derivatives from the Cyclization of 3-Cinnamoyl-2-styrylchromonesjournal article2014-03-27