Medeiros, VeraRainha, NunoPaiva, Lisete S.Lima, ElisabeteBaptista, José2022-03-242022-03-242013-11-21Medeiros, V., Rainha, N., Paiva, L., Lima, E., & Baptista, J. (2013). Bovine milk formula based on partial hydrolysis of caseins by bromelain enzyme: Better digestibility and angiotensin-converting enzyme-inhibitory properties. “International Journal of Food Properties”, 17(4), 806–817. https://doi.org/10.1080/10942912.2012.6756071094-2912http://hdl.handle.net/10400.3/6252A new methodology was developed using bromelain as a proteolytic enzyme for the production of a partially hydrolyzed bovine milk formula, without changing the milk's organoleptic and nutritional properties. This study also revealed that the in vitro angiotensin-converting enzyme inhibition increased in the modified milk as compared with the control sample, showing the highest angiotensin-converting enzyme-inhibitory activity for fractions with molecular weights between 3 and 10 kg mol⁻¹. The Lineweaver-Burk plot revealed that the produced milk formula acted as a non-competitive inhibitor, as determined by high performance liquid chromatography.engACE-inhibitory ActivityBromelainMilk Protein AllergyPartially Hydrolyzed Bovine Milk FormulaPhysicochemical and Microbiological PropertiesRp-Hplc/UvSensory Analysisjournal article2022-01-28cv-prod-268727610.1080/10942912.2012.6756071532-2386000327187600009