Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.3/1347
Título: Association of bovine papillomavirus type 2 (BPV-2) and urinary bladder tumours in cattle from the Azores archipelago
Autor: Resendes, Ana
Roperto, Sante
Trapani, Francesca
Urraro, Chiara
Rodrigues, Armindo
Palavras-chave: BPV-2
E5 Oncoprotein
Bracken Fern
Chronic Enzootic Haematuria
Data: Jun-2011
Editora: Elsevier
Citação: “Research in Veterinary Science”. ISSN 0034-5288. Volume 90, Number 3, June 2011, pp. 526-529(4).
Resumo: Urinary bladder tumours in cattle are caused by chronic ingestion of bracken fern and BPV-1/2 infection. The objective of the present study was to assess if BPV-2 was present in urinary bladder lesions from cattle with chronic enzootic haematuria (CEH) from the Azores archipelago (Portugal), in order to gain further information regarding the epidemiologic distribution of this virus. Samples were analysed using PCR specific primers for BPV-2 DNA and an immunohistochemistry for BPV E5 oncoprotein detection. We found a 28% incidence rate of BPV-2 DNA in different types of tumours and cystitis cases (13 out of 46 samples). Tested positive samples for PCR were also positive for the viral E5 oncoprotein; protein immunolabeling was mainly detected within the cytoplasm of urothelial cells, displaying a juxtanuclear distribution. This is the first report of BPV-2 detection in urinary bladder tumours associated with CEH in cattle from the Azores archipelago.
Descrição: Copyright (c) 2010 Elsevier Ltd. All rights reserved.
Peer review: yes
URI: http://hdl.handle.net/10400.3/1347
ISSN: 0034-5288
Versão do Editor: http://dx.doi.org/10.1016/j.rvsc.2010.02.001
Aparece nas colecções:DBIO - Artigos em Revistas Internacionais / Articles in International Journals

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